Functional Characterization of the Candidate Tumor Suppressor Gene NPRL2/G21 Located in 3p21.3C
نویسندگان
چکیده
منابع مشابه
Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C.
Initial analysis identified the NPRL2/G21 gene located in 3p21.3C, the lung cancer region, as a strong candidate tumor suppressor gene. Here we provide additional evidence of the tumor suppressor function of NPRL2/G21. The gene has highly conserved homologs/orthologs ranging from yeast to humans. The yeast ortholog, NPR2, shows three highly conserved regions with 32 to 36% identity over the who...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2004
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-03-3869